Male Infertility [Sperm Optimisation]

Stem cells are undifferentiated cells that are capable of self renewal. differentiation and repair of tissue due to their capacity for division and differentiation. 

Several preclinical studies have addressed stem cell‐based therapies for the recovery of erectile function following cavernous nerve injury and in Peyronie’s disease, diabetes, aging, and hyperlipidemia. Overall, these studies have shown beneficial effects of stem cell therapy.

What is stem cell therapy?

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Preclinical research into various animal models of ED has highlighted many pathophysiologic mechanisms contributing to ED such as cavernous nerve injury and diabetic models  and over the past decade, there has been considerable interest in stem cell (SC) therapy in the treatment of ED. The regenerative effects of stem cells  are likely achieved by secretion of various growth factors into the blood stream and/or migration of these factors to major pelvic ganglia in addition to cell contact, paracrine signalling system and cellular differentiation.

How ever stem cell therapy is currently not a routinely recommended ED treatment and is not approved by US FDA. The American urological Association(AUA) the European Asociation of Urology(EAU) and the Sexual Medicine Society of North America(SMSNA)consider the approach investigational.

How effective is stem cell therapy for erectile dysfunction?

New clinical trial results show that stem cells can restore sufficient erectile function to allow previously impotent men to have spontaneous intercourse. This is the first time stem cell therapy has produced patients who have recovered sufficient erectile function to enable intercourse.

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